Gene ID Number 1435
Modification Site None
Target Antigen MCSF
Swiss Prot P09603
Subcellular location Lumenal
French translation anticorps
Tested applications IF(IHC-P)
Excitation emission 499nm/519nm
Immunogen range 235-265/554
Concentration 1ug per 1ul
Conjugation Alexa Fluor
Crossreactivity Human, Mouse, Rat
Conjugated with ALEXA FLUOR® 488
Clone Polyclonal antibody
Recommended dilutions IF(IHC-P)(1:50-200)
Purification Purified by Protein A.
Also known as Anti-MCSF PAb ALEXA FLUOR 488
Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Specificity This is a highly specific antibody against MCSF.
Long name MCSF Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Synonyms MCSF; CSF-1; Macrophage colony-stimulating factor 1; M-CSF; Lanimostim; CSF1
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MCSF
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Properties For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-MCSF has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Background of the antigen Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.