GOAT ANTI MOUSE M-CSF Antibody

Alternative name5 N/A

Gene name synonims N/A

Purification method N/A

Host organism Goat

Species reactivity Mouse

Alternative name4 M-CSF

Gene name M-CSF

French translation anticorps

Clonality Polyclonal

Category Antibodies

Immunoglobulin isotype Polyclonal IgG

Clone Polyclonal antibody

Alternative name2 Caprine ANTI Murine M-CSF

Alternative name1 Anti-GOAT ANTI MOUSE M-CSF

Alternative name3 Caprinae ANTI Mus musculus M-CSF

Latin name Capra aegagrus hircus,Mus musculus

Form/Appearance Purified (Purified IgG - lyophilised)

Concentration IgG concentration 1.0mg/ml after reconstitution

Tested for: ELISA (EIA), Western Blot (WB), Functional Assay (FA)

Other gene names Csf1; Csf1; op; Csfm; MCSF; C87615; Csfm; CSF-1; MCSF

Properties If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Other names macrophage colony-stimulating factor 1 isoform 2; Macrophage colony-stimulating factor 1; macrophage colony-stimulating factor 1; osteopetrosis; colony stimulating factor 1 (macrophage); N/A

Additional description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.

Advisory In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Storage and shipping Prior to reconstitution store at +Store productone at +4 degrees Celsius.. After reconstitution For optimal long term storage, productone should be kept at -20 degrees Celsius. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.

Description productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Specificity and cross-reactivity M-CSF This item specifically recognises mouse M-CSF (Macrophage colony-stimulating factor), a potent lineage restricted haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which plays a key role in the regulation of cellular differentiation, proliferation, and the survival of blood monocytes, tissue macrophages and their progenitor cells. _x000D__x000D_Along with sRANKL/CD254/OPGL, M-CSF is essential for osteoclastogenesis, acting through the tyrosine kinase receptor c-fms (colony stimulating factor 1 receptor). A genetic defect in M-CSF is responsible for osteopetrosis in mice (op/op), which are severely deficient in mature macrophages and have a restricted capacity for bone remodelling.