Immunoglobulin isotype IgG1
Host organism Mouse (Mus musculus)
Subcategory Mnoclonal antibodies
Source organism Human (Homo sapiens)
Tested applications: Flow Cytometry (FC/FACS)
Also known as Macrophage Colony Stimulating Factor Receptor
Other gene names CSF1R; CSF1R; FMS; CSFR; FIM2; C-FMS; CD115; FMS
Gene name synonims CSF1R; CSF1R; FMS; CSFR; FIM2; C-FMS; CD115; FMS
Gene name CSF1R; CSF1R; FMS; CSFR; FIM2; C-FMS; CD115; FMS
Purification method Affinity Purified by Protein G affinity chromatography.
Form/Appearance Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with APC.
Species reactivity Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity Recognizes human M-CSFR.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names macrophage colony stimulating factor receptor; Macrophage colony-stimulating factor 1 receptor; macrophage colony-stimulating factor 1 receptor; CSF-1-R; CD115 antigen; FMS proto-oncogene; OTTHUMP00000160525; OTTHUMP00000224093; proto-oncogene c-Fms; macrophage colony stimulating factor I receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; colony stimulating factor 1 receptor; Proto-oncogene c-Fms
Storage and shipping May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius. as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. Freezing APC conjugates will result in a substantial loss of enzymatic activity. APC conjugates are sensitive to light.
Description Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.