Gene ID 1435
Target Protein/Peptide MCSF
Modification site None
Swiss Prot P09603
Subcellular locations Lumenal
Excitation emission 590nm/617nm
Concentration 1ug per 1ul
Conjugated Alexa conjugate 1
Conjugated with ALEXA FLUOR® 594
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Clonality Polyclonal Antibody
Other name Anti-MCSF Polyclonal
Clone Polyclonal Antibodies
Purification method Purified by Protein A.
Also known as MCSF Polyclonal Antibody
Group Polyclonals and antibodies
Type Conjugated Primary Antibody
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Host organism Rabbit (Oryctolagus cuniculus)
Properties For facs or microscopy Alexa 1 conjugate.
Specificity This antibody reacts specifically with MCSF
Modification No modification has been applied to this antibody
Antigen Source KLH conjugated synthetic peptide derived from human MCSF
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Synonyms MCSF; CSF-1; Macrophage colony-stimulating factor 1; M-CSF; Lanimostim; CSF1
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Background information Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.