Anti-MCSF (Polyclonal), ALEXA Fluor 594

Gene ID 1435

Target Protein/Peptide MCSF

Modification site None

Swiss Prot P09603

Subcellular locations Lumenal

Applications IF(IHC-P)

Excitation emission 590nm/617nm

Concentration 1ug per 1ul

Conjugated Alexa conjugate 1

Conjugated with ALEXA FLUOR® 594

Applications with corresponding dilutions IF(IHC-P)(1:50-200)

Clonality Polyclonal Antibody

Other name Anti-MCSF Polyclonal

Clone Polyclonal Antibodies

Purification method Purified by Protein A.

Also known as MCSF Polyclonal Antibody

Group Polyclonals and antibodies

Type Conjugated Primary Antibody

Conjugation Alexa Fluor,ALEXA FLUOR® 594

Host organism Rabbit (Oryctolagus cuniculus)

Properties For facs or microscopy Alexa 1 conjugate.

Specificity This antibody reacts specifically with MCSF

Modification No modification has been applied to this antibody

Antigen Source KLH conjugated synthetic peptide derived from human MCSF

Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Synonyms MCSF; CSF-1; Macrophage colony-stimulating factor 1; M-CSF; Lanimostim; CSF1

Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Background information Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.