Gene ID 1436
NCBI Gene Symbol CSF1R
Swiss-Prot No. P07333
OMIM No. 164770
Reactivity H, M, R
MW (kDa) 107 kDa
Concentration 1 mg/ml
Target Modification Phospho
Immunogen Range 691-740
French translation anticorps
Applications WB IHC ELISA
Unigene No. Hs.586219/Hs.654394
Modification Sites H:Y723 M:Y721 R:Y721
Storage / Stability Stable at -20°C for at least 1 year.
Specificity M-CSF Receptor (Phospho-Tyr723) Antibody detects endogenous levels of M-CSF Receptor only when phosphorylated at Tyr723.
Physical Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized peptide derived from human M-CSF Receptor around the phosphorylation site of Tyr723.
Properties If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Synonyms c-fms; CD115; CSF-1-R; CSF1R; CSFMR; FMS; Fms proto-oncogene; kinase CSFR; M-CSFR; Macrophage colony stimulating factor I receptor precursor
Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Description The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.