Gene ID number 1435
Target Antigen MCSF
Modification site None
Swiss Prot P09603
Subcellular location Lumenal
Tested applications IF(IHC-P)
French translation anticorps
Concentration 1ug per 1ul
Excitation Emission 494nm/518nm
Crossreactivity Human, Mouse, Rat
Additional conjugation Anti-FITC Antibody
Recommended dilutions IF(IHC-P)(1:50-200)
Clone Polyclonal antibody
Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Long name MCSF Polyclonal Antibody, FITC Conjugated
Purification method This antibody was purified via Protein A.
Specificity This is a highly specific antibody against MCSF.
Source KLH conjugated synthetic peptide derived from human MCSF
Synonyms MCSF; CSF-1; Macrophage colony-stimulating factor 1; M-CSF; Lanimostim; CSF1
Crossreactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Storage conditions Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Antigen background Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Properties If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.